Best Natural Alternatives to Adderall 2023: Top 5 OTC Adderall Substitute Pills

Best Natural Alternatives To Adderall Header

Are you looking for alternatives to Adderall? A lot of people are looking for natural alternatives to Adderall these days. The reason why is that Adderall is a prescription medication that is used to treat attention deficit hyperactivity disorder (ADHD). However, it can have serious side effects, such as headaches, dizziness, and trouble sleeping.

Additionally, it is not advisable to take Adderall for long periods, as it can cause more harm than good to your brain health.

Fortunately, some natural alternatives to Adderall can help improve cognitive functioning and mental alertness without the risk of side effects.

These natural Adderall substitutes include powerful herbs and supplements that increase brain energy and mental clarity. Additionally, they can also help to improve the functioning of the central nervous system.

Today, the market is saturated with natural OTC alternatives to Adderall, but we have your back. With a lot of back and forth, we have compiled a list of the best natural Adderall replacements. Read on to know more about the same.

What Are Natural OTC Alternatives to Adderall?

Natural OTC Adderall substitutes are simply a type of alternative supplement that is made without the use of synthetic chemicals or artificial ingredients. This means that they are generally considered safer and more effective than prescription medications since they don’t come with the same risks of side effects.

There are several different natural Adderall replacements available, each of which provides its unique benefits. For instance, some over the counter Adderall substitutes can help to improve focus and concentration, while others may help to reduce anxiety and improve mood.

A Look At The 5 Best Alternatives to Adderall for 2023

The best alternatives have to be as effective as Adderall in improving cognitive function, so it was not easy to sort out the top natural supplements. However, our editorial team has done a commendable job and to find the top natural alternatives to  Adderall. Let’s dive in and see how these supplements can help you:

Mind Lab Pro A brain pill that effectively promotes brain regeneration and ensures optimal oxygenation of the brain cell.
NooCube Brain Productivity One of the top alternatives to Adderall to boost optimal brain functioning and eliminate tiredness.
Performance Lab Mind Formulated by health and fitness enthusiasts, Mind can regulate mood balance and reduce signs of stress.
SANE Vitaae Manufactured by one of the most trusted supplement brands, Vita Efficiently promotes mental clarity.
Modafinil The most popular natural substitute for Adderall, sold under the brand name Provigil, promotes wakefulness.

Mind Lab Pro

Best Natural Alternatives To Adderall 1

Product Overview
Form Of Supplement Brain Pill
Ingredients Used Lion’s Mane Mushroom (500 mg), Citicoline (250 mg), SharpPS® Green (100 mg), Bacopa monnieri (150 mg), Rhodiola rosea (50 mg), N-Acetyl-L-Tyrosine (175 mg), Maritime Pine Bark Extract (75 mg), Suntheanine® L-Theanine (100 mg)
Prescription Requirement None
Money-Back Guarantee 60-day
Pricing Starts at $69.00

Opti Nutra Nutraceuticals, the creator of the Adderall substitute called Mind Lab Pro, has only one vision- to make the world see the benefits of natural supplements. The company is dedicated to providing the highest quality products possible.

They use only natural ingredients that are ethically sourced and apply the latest scientific developments in their manufacturing processes. This commitment to quality has made Opti Nutra one of the most trusted names in the industry.

Mind Lab Pro is an effective alternative to Adderall known for being one of the best natural nootropic brain boosters on the market. Mind Lab Pro cognitive brain function by providing a complete amino acid profile and improving blood flow to the brain. This allows for better oxygenation of brain cells and improved cognitive performance.

In addition, Mind Lab Pro also reduces brain fog and increases mental alertness and clarity. Mind Lab Pro works better than any prescription drug used to treat ADHD and improve cognitive function.

Furthermore, as a natural alternative to Adderall, Mind Lab Pro reduces stress and anxiety. It is vegan, GMO-free, has stimulants, and improves memory recall.

The supplement also ensures proper functioning and availability of brain chemicals. It is made from clinically proven ingredients that support cognitive health and function. An attractive money-back guarantee also backs Mind Lab Pro.

Ever since its release, Mind Lab Pro has been loved by everyone. It gives ADHD medications a run for their money. A genuine customer review says,

“I am a retired professor of music education. This has helped me continue to be mentally alert and complete tasks with more professionalism. My daily tasks are not as numerous as before, but I am able to stay alert and engaged as well as focused on the academic responsibilities that continue during retirement.”

Mind Lab Pro Dosage Instructions

The recommended dosage is 2-4 capsules per day, taken with water, juice, or any other beverage. With just two tablets, Mind Lab Pro can help improve cognitive performance, memory, and concentration, boost brain regeneration, and protect against age-related cognitive decline.

Mind Lab Pro Benefits

  • Increases Alpha Brain Waves: Mind Lab Pro has an impressive amino acid profile designed to increase alpha brain waves. This, in turn, can lead to relaxation and improved cognitive function. The natural Adderall substitute also contains other ingredients claimed to be beneficial for overall brain health. Mind Lab Pro is marketed as an Alternative to Adderall and is said to be helpful for those who suffer from brain fog or mental tiredness.
  • Ensures Proper Oxygenation Of Brain Cells: Mind Lab Pro can help to ensure proper cerebral blood flow and rejuvenate brain cells, which boosts cognitive function and improves brain health. With optimal blood flow and brain energy, Mind Lab Pro can help improve mental performance by providing the nutrients needed for healthy brain function. In addition, the natural OTC Adderall substitute can also help to protect the brain from damage by free radicals and other toxins. By ensuring proper cerebral blood flow and providing the nutrients needed for healthy brain function, Mind Lab Pro can help improve cognitive performance and protect the brain from damage, thus promoting overall brain health.

NooCube Brain Productivity

Best Natural Alternatives To Adderall 2

Product Overview
Form Of Supplement Brain Pill
Ingredients Used Huperzia serrata (20 mg), Bacopa monnieri (250 mg), Lutemax® 2020, Resveratrol 99% (anti-inflammatory), Pterostilbene (140 mcg), L-Theanine (100 mg), Alpha GPC (50 mg), L-Tyrosine (250 mg), and Vitamin B
Prescription Requirement No prescription required
Money-Back Guarantee 60-day
Pricing $59.99

Wolfson Brands UK, the manufacturer of NooCube Brain Productivity, is one of the top health supplement brands in the world. The company is known for its high-quality sports nutrition supplements, pure and quality ingredients, competitive price, and refund policy.

Wolfson Brands UK has grown to become one of the leading health supplement brands in the UK and the USA. Their products are available in over 60 countries worldwide. The company’s vision is to provide safe, effective, affordable supplements to help people achieve their fitness goals.

NooCube Brain Productivity is a natural OTC replacement to Adderall that helps improve brain energy, mental clarity, and cerebral blood flow. It is one of the most popular nootropics on the market today and is used by many people to help improve their cognitive performance.

NooCube effectively improves cognitive function in healthy individuals and those with cognitive impairments.

A customer testimony of Brain Productivity goes,

“Currently, I am pursuing my college and was having difficulties in memorizing all the study stuff. I shared this problem with one of my best friends, who recommended using Noocube to me. At first, I thought it was just another hoax by the company to mint profits. But after using it, it is as if I have fallen in love with Noocube. Over the course of a few months, it has helped me significantly improve my focus and excel in my studies.”

NooCube Brain Productivity Dosage Instructions

Brain Productivity comes in capsule form. The recommended dosage is 2-3 capsules after a meal. NooCube is designed to help improve cognitive function and memory particularly. Some benefits of NooCube include increased mental clarity, focus, and concentration.

NooCube Brain Productivity Benefits

  • Improves Mental Alertness: NooCube is one of the most potent natural brain boosting alternatives to Adderall that has been designed to help improve mental alertness and cognitive function. The supplement contains a blend of essential nutrients and extracts clinically proven to support brain health and enhance mental energy. NooCube has been shown to improve memory, focus, and concentration and can help reduce stress and anxiety levels. The unique blend of ingredients makes NooCube an ideal choice for those looking for a natural way to boost their brain power and enhance their cognitive abilities.
  • Enhances Overall Brain Health: NooCube has been formulated to increase blood flow and oxygenation to the brain, which can improve brain health. The supplement also contains antioxidants and neuroprotectors that help to protect the brain from free radical damage and support healthy cognitive function. NooCube is a safe and effective way to support overall mental health. The supplement is non-addictive and does not interact fatally with other medications.

Performance Lab Mind

Best Natural Alternatives To Adderall 3

Product Overview
Form Of Supplement Brain Pill
Ingredients Used Cognizin (250MG), Sharp-Ps (100MG), L-Tyrosine (250MG), and Maritime Pine Bark Extract (75MG)
Prescription Requirement None
Money-Back Guarantee 30-day
Pricing $69.00

Performance Lab has conducted and compiled years of research-based information to create their natural Adderall substitute, Mind. According to the lab, their supplement is one of the best natural alternatives to Adderall on the market. The company has an excellent brand image and is very customer-centric. Furthermore, their herbal supplements are known for promoting overall health.

Performance Lab Mind is a natural OTC alternative to Adderall that contains only organic components. It is gluten- and soy-free, which has been shown to boost cognitive function. Additionally, it can treat ADHD symptoms and promote brain cell regeneration. Because it is all-natural, it has no withdrawal symptoms.

Performance Lab calls Mind the best alternative to Adderall for several reasons, and one of them is a good customer rating. A customer testimony reads,

“I was having some trouble finding the word I was looking for.” It sometimes felt like something got locked in place, and my brain was going in circles right around the answer I knew but could not vocalize. Very frustrating!! Both my parents had memory issues, one Alzheimer’s, one dementia. So to try to ward that off, and after much research into available supplements, I began taking this product. I love it! ”

Each Performance Lab Mind brain pill is infused with antioxidants to relieve stress and enhance mental clarity.

Antioxidants in Adderall substitutes help to protect brain cells by neutralizing free radicals. This helps reduce inflammation and cell death and improve cognitive function.

Several studies have shown that antioxidants can improve memory recall and other cognitive functions. For example, one study found that an antioxidant supplement improved memory retention in healthy older adults.

Performance Lab Mind Dosage Instructions

It is essential to follow Performance Lab’s dosage instructions regarding Mind. The official website prescribes 1-2 capsules daily to improve cognitive function. This powerful supplement contains a blend of brain-supporting nutrients and nootropics that have been shown to improve brain chemistry, focus, and mental energy levels. The capsules are easy and can be taken with or without food.

Performance Lab Mind Benefits

  • Eliminates Free Radicals: As a natural over the counter alternative for using Adderall, Mind’s free radical scavenging ability is essential because it optimizes cognitive function. The human brain is constantly under attack from free radicals. These are highly reactive molecules that can damage cells and cause inflammation. The body has a variety of mechanisms to protect the brain from free radical damage, but these become less effective as we age. This is why taking steps to reduce free radical damage and boost cognitive brain function is essential.
  • Boosts Brain Chemicals: The natural OTC Adderall substitute can help boost brain chemicals to improve cognitive function. This process is believed to help with brain regeneration, as well as provide a variety of benefits for cognitive functions. Furthermore, Alpha brain waves are increased after taking Mind, which can lead to better cognitive performance. The Mind can also help reduce mental tiredness, improve focus, and reduce anxiety and stress levels.

SANE Vitaae

Best Natural Alternatives To Adderall 4

Product Overview
Form Of Supplement Brain Pill
Ingredients Used Acetyl L-Carnitine HCL, L-Carnitine Tartrate (amino acid), Gymnema Sylvestre, and Omega-3, Citicoline (100mg), and Coenzyme Q-10 (50mg)
Prescription Requirement None
Money-Back Guarantee 365-day money-back guarantee
Pricing $47.00

SANE labs have created Vitaae, one of the top Adderall substitutes. Jonathan Bailor is the CEO of SANE labs, a cutting-edge supplement company dedicated to formulating the best supplements the world has ever seen. Using advanced nutritional knowledge and expertise, SANE labs can develop truly unrivaled products in terms of quality and efficacy.

Under Jonathan’s leadership, SANE labs have become a recognized name in the health and fitness industry thanks to its commitment to innovative product development and excellent customer service.

SANE Vitaae has become the most sought-after natural alternative to Adderall today. With its proprietary blend that includes an excellent amino acid profile, Vitaae effectively helps treat ADHD symptoms and claims to be as effective as prescription medications. The nutrients in Vitaae promote mental energy and reduce brain fog upon regular usage.

If you want to avoid an Adderall addiction, Vitaae is the brain pill you need to start consuming.

SANE Vitaae Dosage Instructions

If you are taking Vitaae capsules, the recommended dosage is two capsules with each meal. This ensures you get the proper nutrition from your food and prevent any deficiency.

SANE Vitaae Benefits

  • Reduces Inflammation: Vitaae is the best alternative to Adderall with anti-inflammatory properties. It can inhibit the production of pro-inflammatory cytokines. This is significant because chronic inflammation has been linked to many diseases, including Alzheimer’s disease, Parkinson’s disease, and stroke. Therefore, by reducing inflammation, Vitaae may help to protect the brain from these degenerative disorders.
  • Enhances Mental Clarity: Vitaae is an effective alternative that has been shown to help improve mental clarity and focus. The unique amino acid profile in this natural alternative helps to support optimal brain function, providing the nourishment needed for clear thinking and quick memory recall. For those struggling with brain fog or mental fatigue, Vitaae can be a welcome addition to their routine, as it can help to increase mental energy and stamina.


Best Natural Alternatives To Adderall 5

Product Overview
Form Of Supplement Brain Pill
Ingredients Used Lactose, Microcrystalline Cellulose, Pregelatinized Starch, Croscarmellose Sodium, Povidone, and Magnesium Stearate
Prescription Requirement Prescription required
Money-Back Guarantee NA
Pricing It starts at $10

Modafinil is a prescription medication that helps to alleviate neuropsychiatric disorders and bad sleep schedules and enhances the central nervous system. It is an effective natural alternative to Adderall and can eliminate brain fog.

Modafinil is sold under the brand name Provigil, which is a drug used to promote wakefulness. It alters brain chemistry and enhances the working of neurotransmitters to treat excessive sleepiness caused by sleep apnea, a condition where people stop breathing for short periods during sleep.

Provigil is classified as a eugeroic medication, meaning it has wake-promoting properties.

Modafinil Dosage Instructions

The recommended dosage of Modafinil is one capsule per day. It is best to take the capsule in the morning, but it can be taken at any time. If you miss a dose, you can take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once.

Modafinil Benefits

  • Improves Working Of The Brain Chemicals: Modafinil is a central nervous system stimulant that is thought to work by enhancing the brain chemicals dopamine and norepinephrine, which are involved in wakefulness. Modafinil has improved insomnia in people with sleep disorders such as narcolepsy and obstructive sleep apnea. It is also used off-label for shift work sleep disorder, attention deficit disorder, and depression.
  • Reduces Stress And Anxiety: Modafinil stimulates dopamine production in the brain, lessening stress and anxiety. Dopamine is a neurotransmitter that plays a vital role in our mood and motivation. When stressed or anxious, our dopamine levels tend to dip, making us feel more tired and down. In addition, Modafinil has also been shown to improve focus and concentration, which can be helpful when we are overwhelmed by life’s demands.

How We Ranked The Best OTC Alternatives to Adderall

Now, let’s look at the parameters we have used to rate the best Adderall OTC alternatives:

Manufacturer Reputation

A manufacturer’s reputation is essential because it tells you how reliable a company is. A company with a good reputation is likely to produce effective and safe products. Trusted brands also tend to have good customer service, so if you have any problems with their products, you’ll be able to get help from them.

The natural over the counter Adderall alternatives above come from reputable and trusted brands. This means you can be confident that they’ll be effective and safe for you. You can contact the companies directly for assistance if you have any questions or concerns about these products.

Third-Party Lab Testing

There are several potential alternatives to Adderall, but not all have undergone third-party lab testing. This means there is no way to verify the safety and efficacy of these alternatives.

The alternatives to Adderall on our list have all undergone third-party lab testing and are, therefore, the best options.

These alternatives are safe and effective in treating ADHD symptoms, so you can be confident that you’re making the right choice for your health.

Manufacturing Details

All of the best replacements to Adderall on our list have been manufactured in FDA-approved and GMP-certified facilities. These are the highest quality facilities available, and they ensure that our products meet all safety and quality standards. These facilities also assure natural Adderall substitutes are made from safe and effective ingredients.

All-Natural Ingredients

The alternatives to Adderall on our list have all been made from natural ingredients and are safe for everyone to consume. Each alternative listed above has been designed to provide the same benefits as the medication itself without the risk of any adverse side effects. Anyone above the age of 18 can use these alternatives.


It is essential to know what is in the supplements you are taking, which is why we appreciate that every natural alternative to Adderall on our list has maintained transparency.

The companies have disclosed all the ingredients in their formulas and provided detailed information about how those ingredients work. This allows consumers to make informed choices about which products are right for them.

We believe that transparency is crucial when it comes to a natural supplement. Too often, companies try to hide the truth about what is in their products or downplay the potential side effects.


All of the natural alternatives to Adderall on our list are GMO-free. This means that they have not been altered in a laboratory and are made from ingredients that come from nature. Some people prefer natural alternatives because they believe these products are safer and more effective than those containing GMOs.

Also, GMOs can be particularly harmful while seeking alternatives to Adderall that directly affect your central nervous system.

Pricing And Refund Policy

If you’re looking for OTC alternatives to Adderall that are both affordable and effective, then you’ll want to check out the options on our list. All the alternatives we’ve listed have reasonable pricing and solid money-back guarantees so that you can feel confident about your purchase. Plus, they’re all made from the safest ingredients, so you can be sure they’re safe to take.

Positive Customer Reviews

When finding an effective and safe alternative to Adderall, it is essential to consider customer reviews. After all, these people have tried the product and can attest to its efficacy. The natural alternatives to Adderall on our list have all received positive customer reviews, which is a good indication that they are trustworthy options. Furthermore, because they are natural alternatives, they are likely to be much safer than traditional Adderall.

The Science For Common Ingredients Used In Alternatives To Adderall

Most of the over-the-counter (OTC) formulations of alternatives to Adderall \contain nutrients, herbs, and herbal extracts that have been studied for their ability to help improve focus and cognitive function. Commonly used ingredients include:

Lion’s Mane Mushroom

The extract from lion’s mane mushrooms contains several bioactive compounds, including terpenes and polysaccharides, with potential therapeutic benefits. Research suggests that these compounds may stimulate the production of nerve growth factor (NGF), which helps facilitate communication between neurons in the brain and can improve cognitive abilities such as learning, memory recall, etc.

Additionally, lion’s mane extract contains potent antioxidants which help postpone cell damage due to aging by scavenging free radicals.

As we age, our brains become more susceptible to oxidative stress, which leads to memory loss and other cognitive impairments. Protecting brain cells with antioxidants can help reduce age-related mental decline.

In a clinical study involving fifty elderly patients with mild dementia, they were given Lion’s Mane Mushroom extract for 16 weeks. The results showed a significant improvement in their overall cognition score compared to those who did not receive any treatment.

Another study investigated the effect of Lion’s Mane extract supplementation in healthy adults aged 51-89 over four months. This study found that those taking the supplement experienced improved cognition scores compared to placebo capsules.

Rhodiola Rosea

Rhodiola rosea is a perennial plant that grows in mountainous regions in Europe, northern Asia, and North America. The root of this plant has been used since ancient times for medicinal purposes and has even been adopted by many traditional Chinese medicine practitioners.

Research suggests that Rhodiola Rosea acts as an antioxidant that helps protect our neurons from damage caused by free radicals formed when we encounter environmental stressors such as physical strain or chemical exposure.

Additionally, there is evidence to suggest that components found in Rhodiola can help to increase neurotransmitter production (such as serotonin), which are thought to aid memory formation and enhance moods.

Furthermore, this herb has also shown signs of reducing inflammation throughout the body, which could benefit overall brain health through the decreased risk of neurodegenerative conditions such as Alzheimer’s disease or Parkinson’s Disease.

A placebo-controlled study published in 2015 showed increased cognitive performance after taking an oral supplement containing Rhodiola over six weeks when compared against control groups who received other conventional medicines, or placebos findings were replicated when they repeated their experiment with a doubled dose range of four weeks later.


Ashwagandha (Withania somnifera) is an ancient herb that has long been used in traditional Ayurvedic medicine to help improve overall health and well-being. It belongs to a group of herbs known as adaptogens, which help the body cope with physical and emotional stressors by regulating hormones such as cortisol.

As mentioned before, ashwagandha is an adaptogen. This means that it can help your body respond better to stress by helping regulate cortisol levels in your system. Studies have shown that low cortisol levels can lead to poor stress management abilities, difficulty concentrating, and lack of motivation, all of which are detrimental to brain health.

Additionally, ashwagandha has also been found to have potential anti-inflammatory properties due to its high antioxidant content – inflammation can be linked with depression, anxiety, and decreased mental performance.

Furthermore, ashwagandha contains compounds such as ginsenosides which help to boost memory and learning retention due to their effect on creating new nerve connections throughout the brain.


Citicoline is an essential nutrient found naturally in the body with several benefits for cognitive functioning. It’s made up of two compounds, cytidine, and choline, which play a role in energy metabolism in cells, especially in the brain. Both components play vital roles in cell growth and membrane integrity, specifically regarding nerve and muscle cells.

Furthermore, research indicates that cytidine enters into the production of phosphatidylcholine (one of the main phospholipids making up cellular membranes).

Citicoline improves focus and mental performance by increasing energy metabolism within neurons. It does this by stimulating the production of phosphatidylcholine, an essential component that helps with memory formation and repair within cell membranes.

As such, it’s thought to be beneficial for some medical conditions such as Alzheimer’s disease or dementia since they are associated with age-related memory decline due to impaired cell membranes or communication pathways between neurons.

Additionally, citicoline has been found to reduce symptoms associated with stroke by inhibiting lipid peroxidation (a significant factor leading to cell death) while enhancing recovery following injury or trauma related to stroke.

Maritime Pine Bark Extract

Maritime Pine Bark Extract, commonly referred to as Pycnogenol®, is made from the bark of a unique tree native to coastal France known as the Maritime pine (Pinus pinaster). It contains potent antioxidant compounds called procyanidins, which are responsible for their remarkable therapeutic properties.

Maritime Pine Bark Extract has various botanical benefits, including anti-inflammatory effects, the suppression of hyperactive immune responses, improved circulation throughout the body through vascular dilation, antioxidative actions due to free radical scavenging activity, protection from UV rays, and more.

Maritime Pine Bark Extract has been studied extensively for its ability to enhance mental performance. One study showed that it could strengthen cognitive function in young adults (aged 18-24 years) and elders (over 65 years) after just four weeks of supplementation at the 150 mg/day dosage used in this study.

Furthermore, several other studies have shown positive results regarding physical task completion times being significantly improved in those participants supplemented with Pycnogenol® compared with placebo groups.

Magnesium Stearate

Magnesium Stearate is a white powder composed of 2 parts: magnesium (Mg) and stearic acid (C18H36O2). It’s found naturally in the body at low levels but is often added to pharmaceutical drugs and supplements to help keep them free-flowing. Magnesium Stearate is also used as an emulsifier or thickener in cosmetics, food preparations, vitamins, and oral medications.

A 2020 meta-analysis analyzed 12 prevalent trials that investigated the effects of oral supplements containing Mgst on cognition health. The results suggested that heightened concentrations of Mgst could “significantly improve cognitive functioning when compared to placebo conditions” over six months after treatment began.

This finding ran parallel with previous Magnetic Resonance Imaging (MRI) scans which showed improvements in hippocampal activation following Mgst supplementation as measured by increased blood oxygen level-dependent (BOLD) signals during verbal fluency tasks.


Research has indicated that Povidone can help improve cognitive functioning and brain health due to its interaction with cell membranes. When this type of molecule interacts with cell membranes, it helps ensure more efficient delivery of vital nutrients into cells, enhancing the communication between neurons and improving cognitive functioning, including memory recall and information processing capacity, among other things.

A study conducted in 2010 found that when rats were administered a low dose of Povidone, they experienced a higher learning rate and improved memory retention compared to those in a control group without any treatment.

Additionally, another study conducted in 2012 observed that changes in neuronal activity patterns could be observed after administering Povidone through advanced imaging techniques.

This indicates that Povidone influences nerve activity throughout the brain, resulting in increased cognitive function patterns indicative of improved overall cognition.


When it comes to promoting brain health and cognition function, there are two main benefits associated with zinc supplementation: 1) neuronal protection/repair; 2) synaptic plasticity enhancement/restoration.

Studies have also found evidence suggesting that zinc might be needed more so during times of heightened stress due to increased cortisol levels within the hippocampus leading to prolonged neuron damage if not replenished.

Interestingly, one study even showed that chronic stress exposure was reduced significantly when patients were treated with dietary supplementation of 40 mg/day of zinc gluconate (as opposed to a placebo group).

There’s been a growing interest from researchers in studying how zinc can help protect against neurodegenerative diseases such as Alzheimer’s disease and dementia. One study out of China found that individuals supplemented with 30 mg/day of zinc for one year had improved episodic memory compared to those given a placebo.

Another study by Johns Hopkins University showed that supplementation with 20mg/day of zinc might help slow down age-related cognitive decline. Finally, another study sponsored by the US NIH found that higher dietary zinc intake was linked to better cognitive performance.

Coenzyme Q10

It has long been thought that CoQ10 may provide benefits to brain health due to its antioxidant abilities which can help protect cells from damage caused by free radicals. It may also play a key role in providing energy to neurons that form memories or carry out various cognitive tasks.

Several studies have evaluated the effects of CoQ10 on participants suffering from various forms of dementia, such as Alzheimer’s or Parkinson’s disease. These studies have generally seen positive results, concluding that supplementation with it leads to improved cognitive performance or reduced symptoms associated with dementia-related conditions.

One study even suggested that taking 100 mg of CoQ 10 daily led to significant changes in cognition compared to those taking placebo at one-year follow-up assessments.

Another double-blind trial showed evidence for enhanced memory recall abilities following supplementation with 300 mg/day for 13 weeks. Further research demonstrated improvements in tests measuring different cognitive skills, such as focus and attention.

Gymnema Sylvestre

Gymnema Sylvestre has been studied for its effectiveness in improving types of memory impairment caused by conditions like Alzheimer’s or dementia. One way it does this may be through flavonoids, antioxidant compounds that fight inflammation associated with cognitive decline.

Additionally, the effects of gymnemic acid mimic insulin-like peptides, which can cause a neuronal protection boost against oxidative stress (free radical damage).

Numerous studies have looked at Gymnema Sylvestre and its effect on cognition in humans and animals, with promising results. In one placebo-controlled trial, 60 participants over 18 years old took either 200mg/day glycine supplementation or a placebo over eight weeks while engaging in cognitive exercises three times weekly.

Results showed that those taking Gymnema Sylvestre had more significant improvement in overall verbal memory scores than those taking a placebo eight weeks after intervention completion.


Omega-3 is a variant of polyunsaturated fatty acids (PUFAs) that include ALA (alpha-linolenic acid), EPA (eicosapentaenoic acid), and DHA (docosahexaenoic acid). Of these three types, EPA and DHA are the most widely researched due to their prevalence in fish oil supplements. PUFAs are essential fatty acids that must be acquired through dietary sources as the body does not make them naturally.

Omega-3 provides essential building blocks for neurons, which can help to create new neural pathways in the brain. Studies have also suggested that omega-3s may help decrease inflammation in the brain, which could lead to improved cognitive function as well as protect against degenerative neurological diseases such as Alzheimer’s or Parkinson’s disease.

Additionally, increasing intake of these fatty acids may elevate levels of serotonin and dopamine – neurotransmitters known to play a role in mood regulation– leading to an improved outlook or general well-being alongside enhanced cognition.

Saw Palmetto

Studies have shown that Saw Palmetto may improve brain health by supporting certain neurotransmitters, such as dopamine and noradrenaline, which help regulate mood. It may also increase levels of acetylcholine, a chemical messenger responsible for memory formation and recall. Saw Palmetto may help protect against damage caused by oxidative stress, which can impair cognitive functioning over time.

A study from 2012 showed that a combination of omega-3 fatty acids (found naturally in saw Palmetto), vitamin B (riboflavin), and zinc improved memory performance in adults aged 55 and older with mild memory complaints compared to those taking placebo pills over 12 weeks.

Another study conducted in 2017 concluded that saw palmetto extract was associated with better global cognition scores compared to placebo in women aged 60–75.

A 2019 meta-analysis found that taking 400mg daily of saw palmetto extract improves spatial orientation skills significantly compared to no supplementation.


Caffeine is an alkaloid in several plants, including coffee beans, tea leaves, cocoa beans, Guarana berries, and Yerba Mate leaves.

Caffeine stimulates certain brain parts when ingested into the human body, increasing energy levels, alertness, and motivation. It helps ward off fatigue and enhances concentration and memory formation while decreasing feelings of physical discomfort.

Caffeine can act as a mild nootropic (smart drug), offering temporary boosts in focus, alertness, and energy levels throughout prolonged mental efforts such as studying or problem-solving.

The primary biological process through which caffeine affects cognitive functioning appears to involve increasing synaptic availability of dopamine in an area of the brain called the striatum, located deep within your gray matter, which may play a key role in reward-based learning.

Alpha GPC

Alpha GPC (Alpha-glycerophosphocholine) is a natural choline found mainly in goat’s milk and soybeans. Choline is an essential nutrient for adults and children; however, it cannot be produced by our bodies naturally, so it must be taken from dietary sources or supplements. It is crucial in many critical metabolic processes, such as memory formation, genetic regulation, and signal processing between neurons.

Alpha GPC helps to increase the levels of acetylcholine in the brain, which support many kinds of mental activities and neurophysiological functions, including learning, alertness, attention span, and memory formation.

Acetylcholine aids communication between nerve cells by binding to receptors on their surfaces, promoting healthy nervous system activities like decision-making and performing complex tasks effectively.

FAQs About Alternatives to Adderall

Q: Why Do People Seek OTC Alternatives to Adderall?

A: People with attention deficit hyperactivity disorder (ADHD) often seek out alternatives  to Adderall because the prescription drug can be addictive and has several potential side effects. Natural alternatives help to improve brain health and cognitive functioning without the risk of Adderall addiction or withdrawal symptoms and, therefore, are very attractive to many people.

Q: Does Adderall Have The FDA’s Approval?

A: Adderall is a prescription drug to treat ADHD symptoms, cognitive decline, and brain fog, improve clarity, and promote brain cell regeneration. The FDA has approved Adderall to treat ADHD symptoms, or other brain health conditions deemed necessary. While Adderall has not been approved explicitly for overall cognitive health, the FDA has found that it is safe and effective when used as directed by a physician.

Q: Are Natural Alternatives to Adderall Safe?

A: Natural alternatives to Adderall are generally safe. However, as with any supplement, it is essential to research the specific ingredients in each product.

Some natural OTC Adderall substitutes contain herbal extracts that may interact with medications you are taking or have other side effects.

Be sure to talk to your healthcare provider before taking any natural Adderall substitute, even if it is generally considered safe.

Q: What Are The Common ADHD symptoms?

A: ADHD, or attention deficit hyperactivity disorder, can cause various symptoms, including brain fog, cognitive decline, and mental fatigue. These symptoms can make it difficult for people with ADHD to concentrate and focus on tasks.

Additionally, people with ADHD may have difficulty controlling impulsive behaviors. Some research suggests that genetic and environmental factors may cause ADHD.

Treatment for ADHD typically involves medication, natural supplements, counseling, and behavior modification.

Q: Do I Need An Adderall Prescription To Buy Alternatives To Adderall?

A: You do not need an Adderall prescription to buy alternatives to Adderall replacements. There are many natural over-the-counter), Adderall OTC alternatives available that can provide the same benefits without requiring a prescription.

These include herbs and supplements such as ginkgo biloba, gotu kola, and Rhodiola rosea. These natural alternatives can help to improve focus and concentration and boost energy levels without the side effects often associated with Adderall.

Q: How Long Should I Consume An Alternative To Adderall To Observe Benefits?

A: There is no one-size-fits-all answer to how long you should consume an alternative of Adderall to observe benefits. The length of time may vary depending on individual factors, such as the severity of your ADHD symptoms and your response to treatment.

Some people may see benefits within a few weeks, while others may need to take the medication for 4-6 months before observing any improvements.

Suppose you don’t see any benefits after six months of treatment. In that case, the natural supplement is likely ineffective, and you should consider trying a different ADHD medication or supplement.

Q: Is A Natural Alternative To Adderall Safe For Everyone?

A: An organic Adderall OTC alternative is generally safe for most people, but some exceptions exist. Pregnant women, children, nursing mothers, and anyone taking other prescription drugs should not take any alternative without consulting their doctor.

An alternative to Adderall can interact with other medications and may not be safe for everyone.

Q: What Health Benefits Can I Receive From An Alternative to Adderall?

A: An alternative to Adderall can provide many health benefits, including boosting your brain’s function, improving brain chemistry, and eliminating brain fog.

Mental clarity, memory recall, and mental energy are also increased with an effective natural alternative to Adderall. Proper cerebral blood flow is another health benefit that can be received from an Adderall OTC alternative.

The 5 Best Alternatives To Adderall for 2023 Final Thoughts

Finding the best alternative to Adderall is a challenging task, especially when Adderall substitutes cost a fortune. However, with our list, you can be assured that you are getting the perfect product to address your attention deficit disorder or any other cognitive decline. So, please don’t wait any longer; try our trusted natural OTC alternatives to Adderall .


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