TRT Dosage Calculator | Injections, Creams, And More

Are you looking for a TRT dosage calculator?

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Do you wonder how much testosterone you should take per week for best results, or whether you should be taking testosterone injections or creams?

Then you’ve come to the right place.

In this comprehensive guide, we cover everything you MUST know about testosterone replacement therapy, including how to optimize your weekly testosterone dosage based on your unique goals and biochemistry.

We also answer your most important questions, including: 

  • What’s the best form of testosterone to take?
  • What’s the difference between testosterone therapy and steroids?
  • What’s the highest amount of testosterone you can take each week?

…And much more! 

Our team of experts at Testosterone.org has analyzed all of the latest research studies to give you science-based answers to all of your most important questions. 

We even cover how often you should inject or take testosterone each week to minimize estrogenic side effects…

Now let’s get started!

P.S: Looking to get started with TRT asap? Click here.

What Is Testosterone Replacement Therapy?

TRT, aka testosterone replacement therapy, is the #1 medical treatment for men suffering from signs and symptoms of low T, or low testosterone levels. 

Testosterone therapy is designed to help men safely raise their total testosterone levels. This helps them eliminate their low T symptoms, including:

  • Low energy
  • Reduced sex drive
  • Depression
  • Weight gain
  • Reduced motivation

Of course, TRT does more than just eliminate your low T symptoms – it also offers countless benefits. 

Men on TRT always say the same thing: they feel like a new man, with limitless energy and a leaner, more athletic-looking physique. 

Let’s quickly cover what testosterone actually is, followed by the reasons why more and more men are suffering from low T in the 2020s…

What Is Testosterone?

Testosterone is sometimes called the “male sex hormone.” It plays a critical role in men’s overall growth and development, but women also need some testosterone for optimal health. 

Research shows that men with above-average testosterone levels experience the following benefits:

  • Increased Muscle Mass
  • Reduced Belly Fat Levels
  • Superior Energy Levels
  • Improved Sexual Performance
  • Elevated Mood / Cognition

As you can see, having high testosterone levels is almost like a “cheat code” in life. 

Men with high testosterone levels are leaner, better looking, and get more attention from the opposite sex. They are also less likely to suffer from chronic illnesses like cardiovascular disease, diabetes, and obesity.

Why Do Men Have Low Testosterone?

Researchers are puzzled by the recent decline in men’s testosterone levels. 

The latest studies show average testosterone levels in men are dropping by about 1% per year, and this trend shows no signs of slowing down [1].

This isn’t just a problem for older men in their 60s, though – studies show that men of all ages (including men in their 40s, 30s, and even 20s!) are suffering from signs and symptoms of low T  [2-4]. 

In fact, some researchers have found a link between men’s declining testosterone levels, and the sudden rise in chronic diseases over the past 50 years [5, 6].

What Are Normal Testosterone Levels In Men?

Men’s testosterone levels are dropping so quickly, that researchers have had to make multiple “revisions” to the reference ranges for men’s testosterone levels. 

In the past the normal reference range was considered 300 – 1,200 ng / dl, or nanograms per deciliter [7-8]. However, the latest guidelines indicate that “normal” testosterone levels in men is only 250 – 800 ng / dl [9-10]! 

This is extremely alarming, as many men start to experience serious side effects when their testosterone levels are in the 300 – 500 ng / dl range [11]. 

If you are a man suffering from low T, then testosterone replacement therapy is your #1 solution. 

Of course, before we talk about how to calculate your optimal TRT dosage, we have to cover what TRT is and how it works.

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Optimal TRT Dosages For Injections, Creams, And More

How do you calculate the optimal TRT dosage for testosterone injections, creams, and other medications? Let’s start by looking at the goals for testosterone therapy, followed by the optimal dosing protocols. 

The primary goal of TRT is to get your total testosterone levels into the optimal 800 – 1,200 ng / dl range. This is where men feel their absolute best, and experience the fewest number of side effects. 

Of course, most men are NOT in this range today. Here are the traditional guidelines for men’s testosterone levels:

  • Optimal: 800 – 1,200 ng / dl
  • Average: 300 – 800 ng / dl
  • Low: <300 ng / dl

Today most men are in the “low” or “average” categories, meaning they are not getting all of the benefits that testosterone has to offer. 

Your goal with TRT should be to take enough testosterone to get you into the desired 800 – 1,200 ng / dl range, but without going over – as going over 1,200 ng / dl means you risk experiencing side effects. 

TRT Dosage Calculator For Testosterone Injections

If you are using testosterone injections, most experienced TRT doctors recommend you take 100 – 200 mg of testosterone per week. 

This is enough for most individuals to bring their total testosterone levels to the desired 800 – 1,200 ng / dl range. 

  • Conservative Dose: 100 mg per week
  • Moderate Dose: 150 mg per week
  • Highest Dose: 200 mg per week

Most TRT doctors prefer to start their patients off with a more conservative 100 – 150 mg per week dose, with 150 mg per week being a nice “sweet spot” for many individuals [12]. 

However, some patients still experience low T symptoms even when taking 100 – 150 mg of testosterone per week, at which point it may be a good idea to increase the dose to 200 mg per week. 

Taking more than 200 mg of testosterone per week is NOT recommended, as this ventures into “mild steroid cycle” territory and increases the risk of side effects [13, 14]. 

It’s also important to nail your testosterone injection frequency. 

For optimal results, you should perform testosterone injections 1-3 times per week. These should be done in equally divided doses. 

For example, if you are taking 150 mg of testosterone per week and injecting 3 times per week, here is what your testosterone injection schedule might look like:

  • Monday: 50 mg of testosterone
  • Wednesday: 50 mg of testosterone
  • Friday: 50 mg of testosterone

Smaller, more frequent testosterone injections often result in more stable blood testosterone levels than larger bolus doses. However, not everyone likes injecting multiple times per week. 

As long as you are injecting at least once per week, you should be OK. 

Injecting once every 2 weeks (or less!) is NOT recommended, as it may result in wild fluctuations in your blood testosterone levels, and more severe side effects.

TRT Dosage Calculator For Testosterone Creams

Optimal dosage guidelines are much more clear-cut for testosterone injections than they are for testosterone creams. 

Overall, most men get their best results using 1-2 “pumps” of the medication 1-2 times per day. Testosterone creams MUST be used at least 1 time per day, ideally twice, as the medication stays in the body for a very short period of time. 

Twice daily applications ensure that your blood testosterone levels stay extremely level throughout the day, which maximizes your results and minimizes your risk for unwanted side effects. 

Of course, each testosterone cream is different, so it’s hard to give a “1 size fits all” answer for testosterone cream dosage guidelines. 

However, 1-2 “pumps” 1-2 times per day is an excellent starting point for most individuals. 

Of course, your experienced TRT doctor will be able to give you more instruction on how to use your testosterone cream for best results.

TRT Dosage Calculator For Other Testosterone Medications

There are various options besides testosterone injections and creams that you can use. 

Here are some of your best options:

  • Testosterone patches
  • Testosterone pellets
  • Testosterone gels

Each of these options has a decent body of research backing their efficacy. However, overall they are far less effective than testosterone injections and creams for testosterone therapy purposes. 

Our recommendation is to stick with what works – testosterone injections and creams! There’s simply no need to go looking into these less effective alternatives.

TRT Dosing Vs Steroid Cycles | What’s The Difference?

You may be wondering about the difference between testosterone dosing for TRT vs steroids. 

The truth is both testosterone replacement therapy and anabolic steroids work by increasing the total testosterone levels in the users body. The main difference between TRT and steroids is how high you are trying to raise your testosterone levels. 

Here is a simple guideline:

  • TRT testosterone levels: 800 – 1,200 ng / dl
  • Steroid testosterone levels: >1,200 ng / dl

The goal of TRT is to raise your total testosterone levels to the 800 – 1,200 ng / dl range, aka the high end of the healthy, normal range for  men. On the other hand, the goal with steroids is to raise your total testosterone levels well above this “natural limit.” 

This gives the user better results in terms of athletic performance, but it also dramatically increases their risk for unwanted side effects. 

Here are some general dosing guidelines for TRT vs steroids:

  • TRT: 100 – 200 mg of testosterone per week
  • Steroids: 250 – 500 mg of testosterone per week

Most men on TRT use around 100 – 200 mg of testosterone per week. 

This is more than enough to get your total testosterone levels into the desired 800 – 1,200 ng / dl range. On the other hand, steroid users are known to use anywhere from 250 – 500 mg of testosterone (or more!) to “blast” their total testosterone to extremely high levels. 

Again, we do NOT recommend anyone perform steroid cycles. 

You can get outstanding results in terms of improved muscle mass and body composition just by running a safe TRT protocol with 100 – 200 mg of testosterone per week. 

However, there is no denying that more aggressive steroid cycles with 250 – 500 mg of testosterone per week are extremely effective for building muscle mass and boosting overall athletic performance.

Testosterone Injections Vs Creams | Pros And Cons

Testosterone injections and creams are 2 of the most common forms of testosterone medications used by men on TRT. 

So how do you know which medication is right for you? In other words, what are the advantages and disadvantages of each of these medications? 

Let’s start by talking about traditional testosterone injections, followed by the newer testosterone creams that many online TRT providers like Fountain TRT are using with some (but not all!) of their patients.

Testosterone Injections

Testosterone injections are often called the “gold standard” treatment option for men with low testosterone levels. 

They have been studied for decades, and the latest research shows they are extremely effective at raising men’s testosterone levels. 

Here are some of the advantages of using traditional testosterone injections:

  • Decades of research studies backing them up
  • Extremely effective at raising men’s testosterone levels
  • Only have to be administered 1-3 times per week
  • Less expensive than testosterone creams

Research shows that testosterone injections produce a very reliable increase in men’s  testosterone levels. 

Unlike testosterone creams, testosterone injections only have to be performed 1-3 times per week for optimal results. This means they don’t even have to be part of your daily routine to be effective. 

Finally, testosterone injections are less expensive than the newer testosterone creams. This makes them a great choice for anyone who is trying to save some money. 

Testosterone Creams

Testosterone creams are one of the newer forms of testosterone medications, and so far they look like a viable contender to replace testosterone injections as the #1 option for men on TRT. 

Here are some of the advantages of testosterone creams:

  • Easy to use and completely painless
  • Fewer side effects than testosterone injections
  • Slightly less complicated than testosterone injections

Testosterone creams are completely painless, which is an obvious plus for anyone who finds testosterone injections to be painful. 

In addition, the latest research shows that testosterone creams actually result in fewer side effects than testosterone injections, as long as they are being applied twice per day. 

Testosterone creams are slightly more expensive than injections, so they aren’t the best budget-friendly option, and they do have to be applied daily. 

However, if you can get over these drawbacks, they are an extremely viable choice for anyone on TRT.

Testosterone Therapy Benefits

You may be wondering what kinds of results you can expect on TRT… is it really as good as everyone says it is? Here’s what you need to know:

Research shows that testosterone therapy has a diverse list of benefits for older and younger men. Some of the most common benefits include improved energy levels, faster recovery from workouts, and improved overall body composition. 

Here is a list of some of the benefits you can expect while on TRT [15-19]:

  • Improved energy levels
  • Increased muscle mass / strength
  • Increased muscle strength
  • More restful sleep
  • Heightened sense of vitality
  • Improved body composition
  • Faster recovery from workouts
  • Stronger bones and joints
  • Healthy heart and blood
  • Decreased Inflammation
  • Improved sexual performance
  • Improved mental health

Talk about a powerful medical treatment for men! Let’s take a closer look at a few of these benefits…

  1. More Restful Sleep

Did you know that men on testosterone therapy actually experience higher-quality sleep? It’s true!

Multiple research studies have found a link between testosterone therapy, and superior sleeping patterns. And this means more energy during the day and superior overall health!

  1. Leaner, More Athletic Physique

Yes, most men on TRT see rapid changes in their overall body composition. 

They lose several pounds of body fat and gain several pounds of muscle mass without any changes to their diet or exercise routine!

  1. Lower Stress And Anxiety

How would you like to have lower stress and anxiety levels? TRT can help. 

Research shows that testosterone therapy actually reduces your perceived stress levels, which means a higher quality of life and reduced risk for chronic diseases.

  1. Greater Workout Performance

Imagine being able to train all-out in the gym, without ever slowing down… with TRT, this is actually possible! 

Men on TRT find they have better performance in the gym, and faster overall recovery outside the gym.

  1. Improved Sexual Health

Stronger erections, increased sexual drive, improved sensations in bed… all of these things are possible once you start TRT. 

And you won’t be the only person to notice – your girlfriend or wife will also be just as excited about the new and improved you…

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Best Online TRT Clinics

You may be wondering what the BEST online TRT clinic is in the United States today. Don’t worry – we’ve got you covered. 

Our team has spent weeks researching and testing all of the best online TRT clinics, and the verdict is clear: Fountain TRT is the #1 online TRT provider in the United States today. 

Here are a few of the reasons why we chose Fountain TRT over their competitors:

  • Dozens of 5-star reviews from verified customers
  • World-class online TRT doctors with decades of experience
  • A fast, streamlined process to get you on TRT as quickly as possible

Fountain TRT is a truly world-class online TRT provider.

Everything about this company is extraordinarily professional, from their easy-to-navigate website, to their unbeatable online TRT doctors and customer service. 

Best of all,  Fountain TRT makes it easy as possible for you to get started on TRT and obtain your very own testosterone prescription. 

All you have to do is follow these 3 steps:

  • Fill out their online questionnaire, and talk to your TRT doctor about your low T symptoms
  • Perform a comprehensive blood test, and go over the results with your doctor
  • Begin using your prescription testosterone medication as directed by your TRT doctor!

That’s it! Fountain TRT truly makes it as easy as possible for men just like you to get started on TRT. 

Don’t worry – you still get a fully customized treatment plan that is modified based on your unique goals and biochemistry. You won’t find any “cookie cutter” TRT programs here! 

Pros

  • Truly world-class customer service
  • The most quailed TRT doctors in the industry
  • Countless 5-star reviews from satisfied customers

Cons

  • Only offers TRT services, cannot replace your PCP

Click here to get started with TRT!

How To Get Started With Testosterone Therapy

If you decide to work with Fountain TRT (our preferred online TRT provider), then getting started with testosterone therapy is as simple as heading to their website and filling out their online questionnaire. 

From there, your experienced online TRT doctor will walk you through the rest of the process. 

If for some reason you don’t want to work with Fountain TRT, then here are the steps you need to follow to get started on TRT:

  1. Contact An Online TRT Clinic, And Fill Out Their Questionnaire

The first step for getting started on testosterone therapy is to fill out your clinic’s online questionnaire. 

The truth is there are 2 different types of TRT clinics in the United States today:

  • Online TRT clinics
  • In-person TRT clinics

In-person TRT clinics have been around forever, but they are slowly being phased out. 

Online TRT clinics let you talk to your doctor from the comfort of your own home using Zoom and other telehealth technologies. This saves you time AND money, which is huge in today’s modern economy. 

If you decide to work with an online TRT clinic, then the first step is to head to their website and fill out their free questionnaire. 

From there, most clinics will help you set up a risk-free appointment with one of their online TRT doctors.

  1. Talk To Your Doctor About Your Signs And Symptoms Of Low T

During your risk-free consultation with your online TRT doctor it’s important to explain the different symptoms you are experiencing. 

Men with low T often suffer from symptoms like:

  • Impaired sexual performance
  • Reduced sex drive
  • Flabby, out of shape physique
  • Low energy levels
  • Mental health problems

…And much more. 

This is also a great time to ask any questions you might have about TRT, including how fast you can expect to see results and what kinds of results other patients are seeing from TRT.

  1. Perform A Comprehensive Blood Test At A Partnered Lab Facility

If your online TRT doctor agrees that you are a good candidate for testosterone therapy, then he will help you schedule a time to have your bloodwork done at one of their partnered lab facilities. 

Getting your bloodwork done is a necessary part of testosterone therapy, as it’s the only reliable way to measure your actual testosterone levels

Your TRT doctor will look at various tests, including:

  • Total testosterone
  • Free testosterone
  • Estradiol
  • Complete blood count
  • Vitamin D
  • Hematocrit
  • Thyroid function

Of course, the most important thing he is looking at is your total testosterone levels. If these are low, then you may be an excellent candidate for testosterone therapy.

  1. Talk To Your Doctor About The Results Of Your Blood Test

After performing your blood test, your online TRT doctor will help you schedule a time to go over the results of your test. Again, the main thing he is looking at is your total testosterone levels.

Here are some general guidelines for testosterone levels in men:

  • Optimal: 800 – 1,200 ng / dl
  • Average: 300 – 800 ng / dl
  • Low: <300 ng / dl

If your total testosterone levels are below 300 ng / dl (or even in the 300 – 800 ng / dl range), then you may be an excellent candidate for TRT. 

  1. Start Using Your New Prescription Testosterone Medication

After you go over the results of your blood test, your online TRT doctor will get to work on making your 100% customized TRT protocol. This will include your prescription testosterone medication, plus anything else that you need to look at feel your best. 

As we already discussed, there are two main types of testosterone medications:

  • Injections
  • Creams

Your doctor will go over the advantages and disadvantages of these (and several others), and help you pick the one that is best for you. 

From there he will have your prescription testosterone medication shipped to your home, so you can start using it right away.

Getting started with TRT is really that easy!

How Expensive Is Testosterone Therapy?

Some people are afraid to get started with testosterone therapy because they think it is too expensive… are these people right, or are they living in a delusional fantasy world? 

The truth is testosterone replacement therapy is extremely affordable. 

Most plans run around $200 – $300 per month, but this can be reduced by working with an affordable online TRT clinic.

Many of today’s newer online clinics offer TRT programs starting for just $99 per month! Using testosterone injections rather than testosterone creams is another easy way to save some money. 

Finally, most online TRT providers are happy to work with all the major insurance providers, like Aetna, United Health, and more. 

If your insurance provider reimburses for TRT services, then you may be able to get 100% of the cost covered!

Does Testosterone Therapy Have Any Side Effects?

Testosterone therapy is one of the safest medical treatments in the world today. 

Research shows that TRT as very few, if any, side effects, and when men do experience side effects, they are usually extremely mild like minor skin irritation [20-22]. 

Of course, TRT is not for everyone. If you have one of the following conditions, then you should probably steer clear of testosterone therapy:

  • Prostate cancer 
  • Male breast cancer
  • Sleep apnea
  • Urinary tract symptoms 
  • Myocardial infarction
  • Congestive heart failure 
  • High red blood cell count
  • Other cardiovascular issues
  • Men planning fertility

These are all contra-indications for testosterone therapy. If you have something like prostate cancer, then TRT may actually make your condition worse. 

Don’t worry – your online TRT doctor will be able to quickly screen you for any contra-indications.

TRT Short Term Side Effects

Here are some of the short-term side effects that you need to watch out for while on TRT:

  • Shrinkage of the testicles
  • Increased aggression and irritability
  • Swelling or tenderness of breasts
  • Acne or oily skin
  • Swelling of the ankles (fluid retention)
  • Difficulty with urination
  • High blood cell counts
  • Hair loss
  • Mood swings
  • Skin irritation

Don’t worry – research shows that these side effects are relatively rare. 

As long as you are following your TRT protocol to a “T”, then you have nothing to worry about.

TRT Long Term Side Effects

Here are some of the most common long-term side effects while on TRT:

  • Cardiovascular disease
  • Strokes and heart attacks
  • Polycythemia
  • Worsening of urinary symptoms
  • Prostate cancer
  • Lowered HDL
  • Low sperm count
  • Reduced fertility

Most men find that their long-term health actually improves while on TRT, so most of these long-term side effects like cardiovascular disease are a non-issue. However, it is possible to experience reduced fertility or polycythemia (among other things) while on TRT. 

Again, if you are working with an experienced online TRT doctor then he will be able to identify these issues before they become a real problem.

Testosterone Therapy Frequently Asked Questions

Here are some of the most frequently asked questions about testosterone replacement therapy.

Am I A Good Candidate For Testosterone Therapy?

Do you have low testosterone levels? Are you suffering from signs and symptoms like depression, low energy levels, and reduced sex drive? Do you just want to enjoy the benefits of having a fully optimized hormonal profile? 

If so, then you may be an excellent candidate for TRT!

What’s The Best Online TRT Provider?

The best online TRT provider is Fountain TRT. This isn’t just our opinion, though – Fountain TRT has dozens of 5-star reviews, proving that customers are blown away by their results! 

We like Fountain TRT because they employ some of the most experienced and qualified TRT doctors in the United States. 

They also have an ultra-streamlined process that helps you get started on TRT as quickly as possible!

How Fast Will I See Results On TRT?

Most men start to see significant changes in how they look and feel within just 1-2 months.

We’re talking improved body composition, improved sex drive, increased self-confidence, and a dramatic increase in attention from the opposite sex… the list goes on and on!

How Often Do I Need To Check In With My Doctor?

Most TRT doctors recommend their patients perform health checkups every 3-6 months. 

This is done to monitor for hidden side effects, including high blood pressure or erythrocytosis (thickening of the blood). This is also a great chance for your doctor to make sure your testosterone levels are truly optimized. 

If necessary, he can increase or decrease your testosterone dose to make sure you are getting the most out of the treatment process.

Once You Start Testosterone Therapy Can You Stop?

Yes – you can always stop testosterone therapy in the future if you are not happy with your results. 

However, most men stay on TRT for life as they are completely blown away by the results!

Is Testosterone Therapy Safe For Older Men?

Yes, testosterone therapy is perfectly safe for older men. 

TRT has very few, if any, side effects, and is widely regarded as one of the safest and most effective medical treatments in the world today.

Why Do Men Have Low Testosterone?

Men can have low testosterone levels for a variety of reasons: poor sleeping habits, a bad diet, lack of exercise, lack of sex, and more. 

Fortunately, testosterone replacement therapy is a simple solution, no matter the cause!

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Side view of young adult athlete practicing start on 100 m, black background, real athlete

Verdict | What’s The Best TRT Dose?

So what’s the verdict… how much testosterone should you take each week?

The truth is most TRT doctors recommend you take 100 – 200 mg of testosterone per week, with 150 mg of testosterone per week being a perfect “starter dose” for many men. 

Of course, this assumes you are using testosterone injections. If you are using a prescription testosterone cream, then 1-2 “pumps” of the cream 1-2 times per day is usually recommended. 

If you are working with an online TRT provider like Fountain TRT, then your testosterone doctor will explain EXACTLY how much medication to take. He will also customize your treatment plan based on your unique goals and biochemistry.

Men who get started with Fountain TRT always say the same thing…

“I wish I contacted them sooner!”

For most men, testosterone replacement therapy is a life-changing medical procedure. If you want to eliminate your low-T symptoms and completely change the way you look and feel, then TRT is for you.

So what are you waiting for?

Contact Fountain TRT today and get ready to look and feel like a whole new man!

References

  • Nieschlag E, Nieschlag S. Testosterone deficiency: a historical perspective. Asian J Androl. 2014 Mar-Apr;16(2):161-8. doi: 10.4103/1008-682X.122358. PMID: 24435052; PMCID: PMC3955324.
  • Liu YJ, Shen XB, Yu N, Shang XJ, Gu YQ, Zuo LD, Xiong CL, Ye Z, Zhou YZ. Prevalence of late-onset hypogonadism among middle-aged and elderly males in China: results from a national survey. Asian J Androl. 2021 Mar-Apr;23(2):170-177. doi: 10.4103/aja.aja_59_20. PMID: 33154202; PMCID: PMC7991815.
  • Braga PC, Pereira SC, Ribeiro JC, Sousa M, Monteiro MP, Oliveira PF, Alves MG. Late-onset hypogonadism and lifestyle-related metabolic disorders. Andrology. 2020 Nov;8(6):1530-1538. doi: 10.1111/andr.12765. Epub 2020 Feb 16. PMID: 31991053.
  • Cohen J, Nassau DE, Patel P, Ramasamy R. Low Testosterone in Adolescents & Young Adults. Front Endocrinol (Lausanne). 2020 Jan 10;10:916. doi: 10.3389/fendo.2019.00916. Erratum in: Front Endocrinol (Lausanne). 2020 Jul 14;11:449. PMID: 32063884; PMCID: PMC6966696.
  • Peterson MD, Belakovskiy A, McGrath R, Yarrow JF. Testosterone Deficiency, Weakness, and Multimorbidity in Men. Sci Rep. 2018 Apr 12;8(1):5897. doi: 10.1038/s41598-018-24347-6. PMID: 29651127; PMCID: PMC5897450.
  • Saad, F., Röhrig, G., Haehling, S. von, & Traish, A. (2016, November 18). Testosterone deficiency and testosterone treatment in older men. Gerontology. Retrieved February 2, 2023, from https://www.karger.com/Article/FullText/452499 
  • Bhasin S, Zhang A, Coviello A, Jasuja R, Ulloor J, Singh R, Vesper H, Vasan RS. The impact of assay quality and reference ranges on clinical decision making in the diagnosis of androgen disorders. Steroids. 2008 Dec 12;73(13):1311-7. doi: 10.1016/j.steroids.2008.07.003. Epub 2008 Jul 17. PMID: 18687348.
  • Solberg HE, PetitClerc C. Approved recommendation (1988) on the theory of reference values. Part 3. Preparation of individuals and collection of specimens for the production of reference values. Clin Chim Acta. 1988 Oct 31;177(3):S3-11. doi: 10.1016/0009-8981(88)90074-5. PMID: 3233768.
  • Snyder PJ, Bhasin S, Cunningham GR, Matsumoto AM, Stephens-Shields AJ, Cauley JA, Gill TM, Barrett-Connor E, Swerdloff RS, Wang C, Ensrud KE, Lewis CE, Farrar JT, Cella D, Rosen RC, Pahor M, Crandall JP, Molitch ME, Cifelli D, Dougar D, Fluharty L, Resnick SM, Storer TW, Anton S, Basaria S, Diem SJ, Hou X, Mohler ER 3rd, Parsons JK, Wenger NK, Zeldow B, Landis JR, Ellenberg SS; Testosterone Trials Investigators. Effects of Testosterone Treatment in Older Men. N Engl J Med. 2016 Feb 18;374(7):611-24. doi: 10.1056/NEJMoa1506119. PMID: 26886521; PMCID: PMC5209754.
  • Basaria S, Harman SM, Travison TG, Hodis H, Tsitouras P, Budoff M, Pencina KM, Vita J, Dzekov C, Mazer NA, Coviello AD, Knapp PE, Hally K, Pinjic E, Yan M, Storer TW, Bhasin S. Effects of Testosterone Administration for 3 Years on Subclinical Atherosclerosis Progression in Older Men With Low or Low-Normal Testosterone Levels: A Randomized Clinical Trial. JAMA. 2015 Aug 11;314(6):570-81. doi: 10.1001/jama.2015.8881. PMID: 26262795.
  • Testosterone, aging, and the mind. Harvard Health. (2008, January 1). Retrieved February 2, 2023, from https://www.health.harvard.edu/newsletter_article/testosterone_aging_and_the_mind 
  • Borst SE, Mulligan T. Testosterone replacement therapy for older men. Clin Interv Aging. 2007;2(4):561-6. doi: 10.2147/cia.s1609. PMID: 18225456; PMCID: PMC2686341.
  • Chegeni, R., Pallesen, S., McVeigh, J. et al. Anabolic-androgenic steroid administration increases self-reported aggression in healthy males: a systematic review and meta-analysis of experimental studies. Psychopharmacology 238, 1911–1922 (2021). https://doi.org/10.1007/s00213-021-05818-7
  • Albano GD, Amico F, Cocimano G, Liberto A, Maglietta F, Esposito M, Rosi GL, Di Nunno N, Salerno M, Montana A. Adverse Effects of Anabolic-Androgenic Steroids: A Literature Review. Healthcare (Basel). 2021 Jan 19;9(1):97. doi: 10.3390/healthcare9010097. PMID: 33477800; PMCID: PMC7832337.
  • Kim SH, Park JJ, Kim KH, Yang HJ, Kim DS, Lee CH, Jeon YS, Shim SR, Kim JH. Efficacy of testosterone replacement therapy for treating metabolic disturbances in late-onset hypogonadism: a systematic review and meta-analysis. Int Urol Nephrol. 2021 Sep;53(9):1733-1746. doi: 10.1007/s11255-021-02876-w. Epub 2021 Jun 5. PMID: 34089171.
  • Kim SH, Park JJ, Kim KH, Yang HJ, Kim DS, Lee CH, Jeon YS, Shim SR, Kim JH. Efficacy of testosterone replacement therapy for treating metabolic disturbances in late-onset hypogonadism: a systematic review and meta-analysis. Int Urol Nephrol. 2021 Sep;53(9):1733-1746. doi: 10.1007/s11255-021-02876-w. Epub 2021 Jun 5. PMID: 34089171.
  • Lunenfeld B, Mskhalaya G, Zitzmann M, Corona G, Arver S, Kalinchenko S, Tishova Y, Morgentaler A. Recommendations on the diagnosis, treatment and monitoring of testosterone deficiency in men. Aging Male. 2021 Dec;24(1):119-138. doi: 10.1080/13685538.2021.1962840. PMID: 34396893.
  • Varanoske AN, Margolis LM, Pasiakos SM. Effects of Testosterone on Serum Concentrations, Fat-free Mass, and Physical Performance by Population: A Meta-analysis. J Endocr Soc. 2020 Jul 3;4(9):bvaa090. doi: 10.1210/jendso/bvaa090. PMID: 32864543; PMCID: PMC7444672.
  • Traish A. Testosterone therapy in men with testosterone deficiency: Are we beyond the point of no return? Investig Clin Urol. 2016 Nov;57(6):384-400. doi: 10.4111/icu.2016.57.6.384. Epub 2016 Nov 7. Erratum in: Investig Clin Urol. 2017 Jan;58(1):77. PMID: 27847912; PMCID: PMC5109795.
  • Bhasin S. Testosterone replacement in aging men: an evidence-based patient-centric perspective. J Clin Invest. 2021 Feb 15;131(4):e146607. doi: 10.1172/JCI146607. PMID: 33586676; PMCID: PMC7880314.
  • Twitchell DK, Pastuszak AW, Khera M. Controversies in Testosterone Therapy. Sex Med Rev. 2021 Jan;9(1):149-159. doi: 10.1016/j.sxmr.2020.09.004. Epub 2020 Dec 9. PMID: 33309270.
  • Dubin, J.M., Fantus, R.J. & Halpern, J.A. Testosterone replacement therapy in the era of telemedicine. Int J Impot Res 34, 663–668 (2022). https://doi.org/10.1038/s41443-021-00498-5

 

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