Best Joint Supplements 2022/2023: Top Rated OTC Joint Support

The most prevalent joint problem in the United States is arthritis, and knees are frequently the first to be impacted.

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According to one research, more than 10% of men and 13% of women over the age of 60 reported symptoms of knee arthritis.

Prescription painkillers can provide short-term comfort, but they frequently have negative effects. Heart issues and renal damage are among these negative effects.

According to statistics from the Centers for Disease Control and Prevention released in 2006, about 20% of Americans report experiencing knee discomfort in some capacity (CDC). Mild stiffness to very incapacitating degrees of pain are all possible.

That’s where joint supplements come in.

When looking for the Best Joint Supplement, it can be difficult to choose the right product in the vast sea of options out there…

…Some supplements may contain ingredients with no proven benefits for joint health, others may contain clinically proven ingredients…

Luckily for you, we’ve consulted with doctors and physios to form the a list of the best 3 joint supplements on the market right now:

Physio Flex Pro: Best Joint Supplement Overall

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If you are looking for the top joint supplement out there that has helped thousands of customers move freely without pain, Physio Flex Pro is the product for you.

Physio Flex Pro is frequently recommended by leading physical therapists, which says volumes about its caliber and efficacy.

Through the use of evidence-based ingredients, Physio Flex Pro encourages joint lubrication, strengthening, protection, and pain relief. It is prepared to assist patients with groaning and hurting joints since it is made entirely of natural substances. The substances nourish and lubricate the joints to promote strong bones.

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Physio Flex Pro Ingredients

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If you haven’t conducted any prior study into joint support, glucosamine may be one of the more “unknown” substances, but it’s still an important element that you should always check for.

This is due to its natural presence in tendons, ligaments, and cartilage throughout your body. All of these elements are crucial for your body’s mobility and surround your joints.

In essence, taking glucosamine supplements enables you to maintain lubrication in your joints, much as maintaining lubrication in mechanical parts to make them move more easily and prevent rusting.

In addition, studies have shown that glucosamine has additional advantages; one such research indicated that daily glucosamine consumption was associated with a decreased risk of cardiovascular disease [1].


Continuing from where we left off before, we’re thrilled to see the addition of chondroitin. This demonstrates that Physio Flex Pro actually does extensive study before producing their goods.

This is why: Numerous studies have demonstrated that the combination of chondroitin and glucosamine significantly reduces pain and joint space constriction [2]. especially people with osteoarthritis of the knee.

There are other sources as well. Another research found that the combination of chondroitin and glucosamine was much more beneficial than a placebo in reducing pain and enhancing physical function [3].

If you’re curious, chondroitin works by keeping your cartilage and joints ideally lubricated, functioning as a “shock absorber” similar to the suspensions on a car.


Even if you haven’t looked into supplements, everyone is aware of the advantages of turmeric.

It is well recognized for having significant amounts of the antioxidant curcumin. Clinical research have demonstrated curcumin to enhance joint health, and one study even came to the conclusion that taking supplements of curcumin was just as beneficial as taking analgesics in terms of joint pain and bodily function [4].

Of course, since turmeric is all natural and doesn’t have any negative side effects as the chemicals in painkillers do, taking it in joint supplements is far healthier than using them.

All things considered, this is a wonderful addition to joint supplements that we usually seek for when selecting a product.


MSM, or methylsulfonylmethane, is a substance that naturally exists in people, animals, and plants.

It’s an essential component of all joint support supplements because of its capacity to delay cartilage degradation, which protects your joints.

A fascinating research that demonstrates its efficacy was carried out in 2017. MSM supplementation was employed in this study on participants who had just completed a half-marathon, and the findings revealed that it might speed up muscle recovery and lessen joint discomfort [5].

Another research from 2006 that came to the conclusion that MSM might enhance physical performance and pain symptoms without having any negative side effects is evidence of its efficacy [6].

For all of these reasons, MSM is still a component we constantly search for when looking for the best joint supplement.


A wonderful joint supplement called bromelain is a naturally occurring enzyme found in small amounts in plants like pineapples. Numerous health advantages are attributed to bromelain. It has  strong scientific backing in reducing joint discomfort.

Because of its anti-inflammatory properties, bromelain is quite helpful for those who have joint discomfort. This is quite impressive since it demonstrates why bromelain is the finest joint supplement that has ever been created. About 300mg of bromelain are contained in each serving of Physio Flex Pro.

Physio Flex Pro Summary

Physio Flex Pro costs $58 per bottle at the moment, which may seem a bit excessive for some buyers at first glance. However, the cost of this supplement is quite justified when you consider all of its health advantages and when looking at the amount of scientifically backed ingredients in its formula.

Additionally, you might start to feel all the benefits in less than a month – and everyone knows that you get what you pay for; some good news is that there are multi-bottle deals that reduce the cost of each bottle, where you can save up to 10% on their official website.

After being rated highly by thousands of real customers and backed by world leading physiologists, we’re happy to recommend Physio Flex Pro as the #1 joint supplement available right now.

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Performance Lab Flex: Best Joint Supplement for Athletes

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A joint supplement called Performance Lab Flex offers an easy-to-digest combination of “ultramodern” joint nutrients that are said to calm and protect sore joints while promoting joint lubrication, cartilage repair, and long-term joint health and flexibility.

Performance Lab Flex contains a blend of ingredients for joint health. These ingredients are designed to promote joint health and reduce joint aches and pains. Chondroitin sulfate and methylsulfonylmethane are key components for joint health. Chondroitin helps rebuild cartilage by acting like a sponge and retaining water within the cartilage. These ingredients also aid in the production of collagen, an important component of cartilage.

This all-natural supplement is suitable for people with arthritis and joint problems. It combines glucosamine and chondroitin with herbs and nutrients to support the joints, tendons, and ligaments. In addition, it prevents free radicals from damaging joints and other connective tissue. Moreover, it is vegan friendly and suitable for all ages and dietary preferences.

The ingredients used in Flex help reduce joint pain, stiffness, and aches. They act as a shield against free radicals and unnecessary enzymes, while promoting bone density and strength. Moreover, the ingredients used in this supplement have been clinically tested and are of the highest quality.

Performance Lab Flex Ingredients:

  • Glucosamine
  • Chondroitin
  • Methylsulfonylmethane
  • Turmeric
  • Boswellia
  • Strontium

Performance Lab Flex Summary

Performance Lab Flex has six components. This is not a terrible number, but also not as excellent value as Physio Flex Pro, which contains 8 ingredients in its formula.

In terms of facts and figures, Physio Flex Pro also includes Bioperine (black pepper extract), whereas Performance Lab Flex does not. Black pepper extract is significant because it can increase bioavailability, which means that it aids in the digestion of other ingredients when taken with it, enhancing the overall effectiveness of the supplement.

It’s for reasons like this that we think Physio Flex Pro ranks as the top option among these three for joint supplements. But Performance Lab Flex still remains a good second choice.

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SRS Omega Pro: Best Omega 3 Supplement for Joints

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With the most up-to-date and thoroughly researched collection of natural components, SRS Omega Pro provides you with a natural pain relief and mobility help. Guaranteed.

Krill oil is a far better and stronger way to get Omega 3 into your body and experience the advantages it brings than omega 3 from mussels or other fish extracts because it delivers a complete set of high strength, quickly absorbed Omega 3’s in the form of phospholipids.

If you haven’t already noticed, that’s where SRS Omega Pro differs from both Physio Flex Pro and Performance Lab Flex; it’s a dedicated Omega 3 supplement.

Of course, countless studies have proven Omega 3 very beneficial for joint health. And at $28 per bottle (1 month supply), it’s also the cheapest option on this list for those on a budget.

The other added benefit of SRS Omega 3 is that it can be even more beneficial when taken alongside Physio Flex Pro or Performance Lab Flex.

SRS Omega Pro Ingredients:

  • Krill Oil – 500mg
    • EPA, DHA and Astaxanthin

SRS Omega Pro Summary

SRS Omega Pro is made with quality krill oil, which has been demonstrated to have a higher bioavailability than other types of omega 3. It has a higher likelihood of providing you with the advantages you require.

High concentrations of EPA and DHA found in SRS Omega Pro support healthy joints, a strong heart, and can lessen the body’s production of chemicals and compounds connected to inflammation. These pro-inflammatory eicosanoids and cytokines can be reduced, which can ease discomfort and improve mobility.

Additionally, SRS Omega Pro has a plethora of antioxidants, which can help persons with a variety of ailments maintain their general health and wellbeing.

SRS Omega Pro is beneficial taken on its own, or when stacked along with Physio Flex Pro for even better results.

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Do Any Joint Supplements Really Work?

Quick Answer

Yes, but only if you choose correctly. Look for a product that uses substances that have scientific backing and is dosed effectively (but easily ingested). To ensure that the active substances can truly shine through and provide joint support as intended, give preference to goods with a low additive and synthetic content.

The good news is that we’ve conducted the research for you and provided the top 3 joint supplements on the market in this article.

Long Answer

While there are many joint supplements on the market, not all of them offer the same benefits. One of the most important factors in determining whether a supplement works for you is the ingredients list.

Some supplements contain ingredients that have no proven benefits for joint health. Others contain just a small handful of ingredients. Another important factor is to check if the supplement will interact with other medications you’re taking. Blood thinners, for example, may interact with some supplements.

The best supplements are formulated to target the causes of joint pain. Many of them contain antioxidants that can reduce inflammation and pain. Bromelain, for example, is a powerful anti-inflammatory. Research suggests that bromelain can be as effective as diclofenac in relieving joint pain.

The top joint supplement with great reviews is Physio Flex Pro. This product contains seven natural ingredients that are claimed to improve joint health, reduce pain, and improve range of motion. This product also contains turmeric, a common spice used in Indian cuisine that has many benefits for the body. Turmeric, in particular, reduces inflammation and helps reduce pain and stiffness in the joints. It also helps with cartilage metabolism, which can help improve joint function.

>> Get the Best Deal for Physio Flex Pro Here <<

How to Choose a Top Rated Joint Supplement

There are several things to keep in mind when choosing a top-rated joint supplement. Firstly, you need to compare the list of ingredients in each capsule. Some of the supplements contain inactive ingredients that are not beneficial for joint health. Others may contain too few ingredients. Also, you should be aware of any potential interactions with other medications. For example, if you are taking blood thinners, you should check whether the supplement contains the same ingredient.

Another important thing to know about joint supplements is that there is limited research on their effects. However, a few studies have shown that they can help improve the overall health of the joints. This is because joint supplements help improve the surrounding tissues that surround the joints. If these tissues become damaged, or tightened, the joint becomes more difficult to move.

The Arthritis Foundation recommends that you visit a doctor if you’re suffering from chronic joint pain. Your doctor can recommend a joint supplement that is effective for your condition. However, it’s important to check with your doctor about dosage, side effects, and any interactions.

Scientific Studies on Joint Supplements

There are many claims about joint supplements, but there are few scientific studies to back them up. The two most popular supplements are chondroitin sulfate and glucosamine. Both of these ingredients are believed to help reduce joint pain and stiffness, but there are concerns that the supplements may not work as well as advertised. In addition, they vary in bioavailability, making it difficult for consumers to decide which is best for them.

Scientific studies of joint supplements have come up with mixed results. While some supplements are touted as a way to treat joint pain, the American Academy of Orthopaedic Surgeons and Arthritis Foundation both say that they do not provide better results than a placebo. However, the Arthritis Foundation and other organizations say that joint supplements can be useful for relieving arthritis symptoms.

Collagen is an ingredient that has shown promising results in studies on arthritis. Collagen is part of the cartilage that protects our bones and plays a major role in joint and ligament health.

Conclusion on the Best Joint Supplements

Movement is made possible by your joints, and the right joint supplement will support them during all of their demanding job by keeping them strong, pleasant, and healthy. The top joint supplements, like those on this list, will have scientifically-backed substances at dosages that work.

By combining your supplement with other joint-healthy practices like being active (particularly with low-impact exercises), getting enough sleep, and adhering to a healthy diet, you can increase the likelihood that it will be effective for you. Antioxidant-rich foods like salmon, sardines, anchovies, berries, and almonds will be especially beneficial for powering through life’s ups and downs.

Here are the top 3 joint supplements (over the counter) for knee joint pain, arthritis, inflammation and more:


  1. H, Ma. Association of habitual glucosamine use with risk of cardiovascular disease: prospective study in UK Biobank. BMJ 2019; 365: l1628.
  2. M, Fransen. Glucosamine and chondroitin for knee osteoarthritis: a double-blind randomised placebo-controlled clinical trial evaluating single and combination regimens. Ann Rheum Dis. 2015 May; 74(5): 851-8.
  3. X, Zhu. Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials. J Orthop Surg Res. 2018; 13: 170.
  4. K, Paultre. Therapeutic effects of turmeric or curcumin extract on pain and function for individuals with knee osteoarthritis: a systematic review. BMJ Open Sport & Exercise Medicine 2021; 7: e000935.
  5. ED, Withee. Effects of Methylsulfonylmethane (MSM) on exercise-induced oxidative stress, muscle damage, and pain following a half-marathon: a double-blind, randomized, placebo-controlled trial. J Int Soc Sports Nutr 14, 24 (2017).
  6. LS, Kim. Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthritis Cartilage. 2006 Mar; 14(3): 286-94.

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